Annotation Detail

Information
Associated Genes
EPHB2
Associated Variants
EPHB2 MUTATION
EPHB2 MUTATION
Associated Disease
lymphoma
Source Database
DisGeNET
Description
We discovered that YC-1 induces apoptosis and inhibits tumour growth of breast cancer cells via down-regulation of EZH2 by activating c-Cbl and ERK.
Pubmed
24697523
Section of the abstract supporting the evidence
CONCLUSION AND IMPLICATIONS
Number of the section of the abstract supporting the evidence
4
Number of the sentence supporting the evidence
13
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00081432561624091
Drugs