Annotation Detail

Information
Associated Genes
IFIH1
Associated Variants
IFIH1 p.Ala946Thr (p.A946T) ( ENST00000648433.1, ENST00000649979.2, ENST00000679938.1 )
rs1427676
IFIH1 p.Ala946Thr (p.A946T) ( ENST00000648433.1, ENST00000649979.2, ENST00000679938.1 )
rs1427676
Associated Disease
Diabetes Mellitus, Insulin-Dependent
Source Database
DisGeNET
Description
Evidence for association with T1D was observed for the IFIH1 SNP, rs1990760 (P=7.0 x 10(-4)), with RR=0.88 (0.82-0.95) and the CTLA4 SNP rs1427676 (P=0.0005), with RR=1.14 (1.06-1.23).
Pubmed
19956106
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.167448922050564
Year of publication
2009
Drugs