Annotation Detail
Information
- Associated Genes
- TMBIM4
- Associated Variants
-
FTO c.46-43098T>C
(
ENST00000471389.6,
ENST00000637969.1,
ENST00000637001.1,
ENST00000636491.1,
ENST00000636218.1 )
rs17782313
FTO c.46-43098T>C ( ENST00000471389.6, ENST00000636218.1, ENST00000636491.1, ENST00000637001.1, ENST00000637969.1 )
rs17782313 - Associated Disease
- obesity
- Source Database
- DisGeNET
- Description
- In the present study, we analyzed independent and combined effects of the FTO rs1421085 and MC4R rs17782313 risk alleles on BMI, fat mass, prevalence and incidence of obesity and subsequent type 2 diabetes (T2D) as well as their interactions with physical activity levels and gender in two European prospective population-based cohorts of 4,762 Finnish adolescents (NFBC 1986) and 3,167 French adults (D.E.S.I.R.).
- Pubmed
- 19255736
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2009
Drugs