Annotation Detail

Information
Associated Genes
FTO
Associated Variants
FTO c.46-43098T>C ( ENST00000471389.6, ENST00000637969.1, ENST00000637001.1, ENST00000636491.1, ENST00000636218.1 )
FTO c.46-43098T>C ( ENST00000471389.6, ENST00000636218.1, ENST00000636491.1, ENST00000637001.1, ENST00000637969.1 )
Associated Disease
obesity
Source Database
DisGeNET
Description
Obesity risk alleles at FTO rs1421085 significantly predicted more eating episodes per day (P = 0.001)-an effect that persisted after adjustment for body weight (P = 0.004).
Pubmed
22513296
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.4
Year of publication
2012
Drugs