Annotation Detail

Information
Associated Genes
CENPE
Associated Variants
CENPE p.Lys1355Glu (p.K1355E) ( ENST00000265148.9, ENST00000380026.8 )
CENPE p.Asp933Tyr (p.D933Y) ( ENST00000265148.9, ENST00000380026.8 )
CENPE p.Asp933Asn (p.D933N) ( ENST00000265148.9, ENST00000380026.8 )
CENPE p.Lys1355Glu (p.K1355E) ( ENST00000265148.9, ENST00000380026.8 )
CENPE p.Asp933Tyr (p.D933Y) ( ENST00000265148.9, ENST00000380026.8 )
CENPE p.Asp933Asn (p.D933N) ( ENST00000265148.9, ENST00000380026.8 )
Associated Disease
Microcephaly 13, primary, autosomal recessive
Source Database
DisGeNET
Description
Mutations in CENPE define a novel kinetochore-centromeric mechanism for microcephalic primordial dwarfism.
Pubmed
24748105
Original source reporting the Gene Disease association
UNIPROT
DisGENET score for the Gene Disease association
0.12
Year of publication
2014
Drugs