Annotation Detail

Information
Associated Genes
TERT
Associated Variants
TERT p.Val791Ile (p.V791I) ( ENST00000310581.10, ENST00000334602.10 )
TERT p.Val791Ile (p.V791I) ( ENST00000310581.10, ENST00000334602.10 )
Associated Disease
Pulmonary fibrosis and/or bone marrow failure, Telomere-related, 1
Source Database
DisGeNET
Description
Ancestral mutation in telomerase causes defects in repeat addition processivity and manifests as familial pulmonary fibrosis.
Pubmed
21483807
Original source reporting the Gene Disease association
UNIPROT
DisGENET score for the Gene Disease association
0.24
Year of publication
2011
Drugs