Annotation Detail

Information
Associated Genes
ABCA1
Associated Variants
ABCA1 p.Ala1046Asp (p.A1046D) ( ENST00000374736.8, ENST00000678995.1 )
ABCA1 p.Arg230Cys (p.R230C) ( ENST00000374736.8, ENST00000423487.6, ENST00000678995.1 )
ABCA1 p.Ala1046Asp (p.A1046D) ( ENST00000374736.8, ENST00000678995.1 )
ABCA1 p.Arg230Cys (p.R230C) ( ENST00000374736.8, ENST00000423487.6, ENST00000678995.1 )
Associated Disease
Hypoalphalipoproteinemia, Familial
Source Database
DisGeNET
Description
With these new sequencing primers, we found 3 novel ABCA1 mutations: a frameshift mutation (4570insA, A1484S-->X1492), a missense mutation (A986D) in a TD family, and a missense mutation (R170C) in aboriginal subjects with FHA.
Pubmed
10938021
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.366243163057847
Year of publication
2000
Drugs