Annotation Detail
Information
- Associated Genes
- NFKB1
- Associated Variants
-
rs28362491
rs28362491
NR1H2 c.-19-103T>C ( ENST00000253727.10, ENST00000411902.6, ENST00000593926.5, ENST00000598168.5, ENST00000599105.5, ENST00000652203.1 )
NR1H2 c.927+181T>C ( ENST00000253727.10, ENST00000411902.6, ENST00000593926.5, ENST00000598168.5, ENST00000599105.5, ENST00000652203.1 )
ENSG00000285585 c.*2-25037C>A ( ENST00000393716.8, ENST00000466380.6 )
ENSG00000285585 c.*2-24111G>A, NR1I2 c.95+266G>A ( ENST00000337940.4, ENST00000466380.6, ENST00000393716.8 )
NR1H2 c.-19-103T>C ( ENST00000253727.10, ENST00000411902.6, ENST00000593926.5, ENST00000598168.5, ENST00000599105.5, ENST00000652203.1 )
NR1H2 c.927+181T>C ( ENST00000253727.10, ENST00000411902.6, ENST00000593926.5, ENST00000598168.5, ENST00000599105.5, ENST00000652203.1 )
ENSG00000285585 c.*2-25037C>A ( ENST00000393716.8, ENST00000466380.6 )
ENSG00000285585 c.*2-24111G>A, NR1I2 c.95+266G>A ( ENST00000337940.4, ENST00000393716.8, ENST00000466380.6 ) - Associated Disease
- ulcerative colitis
- Source Database
- DisGeNET
- Description
- Genotypes of nuclear factor (NF)-κB (NFKB1) NFκB -94ins/del (rs28362491); peroxisome proliferator-activated receptor (PPAR)-γ (PPARγ) PPARγ Pro12Ala (rs 1801282) and C1431T (rs 3856806); pregnane X receptor (PXR) (NR1I2) PXR A-24381C (rs1523127), C8055T (2276707), and A7635G (rs 6785049); and liver X receptor (LXR) (NR1H2) LXR T-rs1405655-C and T-rs2695121-C were assessed in a Danish case-control study of 327 Crohn's disease patients, 495 ulcerative colitis (UC) patients, and 779 healthy controls.
- Pubmed
- 21245992
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.131258600408795
- Year of publication
- 2011
Drugs