Annotation Detail
Information
- Associated Genes
- MMP12
- Associated Variants
-
MMP12 MUTATION
MMP12 MUTATION - Associated Disease
- Chronic Obstructive Airway Disease
- Source Database
- DisGeNET
- Description
- We compared the frequency of single nucleotide polymorphisms in genes coding for matrix proteinases (MMP1, MMP2, MMP3, MMP9, MMP12) as well as tissue inhibitor of metalloproteinases (TIMP1) in two groups of subjects: COPD patients (54 subjects) and COPD patients diagnosed for lung cancer occurrence (53 subjects).The levels of the respective proteins in blood serum were also analyzed.
- Pubmed
- 25292126
- Section of the abstract supporting the evidence
- MATERIALS AND METHODS
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 4
- Original source reporting the Gene Disease association
- BeFree,GAD,LHGDN
- DisGENET score for the Gene Disease association
- 0.0247323430559516
Drugs