Annotation Detail
Information
- Associated Genes
- MDM4
- Associated Variants
-
USP7 c.2719-234C>T
(
ENST00000344836.9,
ENST00000673704.1,
ENST00000381886.8 )
MDM4 c.-36+2641G>C ( ENST00000614459.4, ENST00000454264.6, ENST00000612738.4, ENST00000367183.7, ENST00000391947.6, ENST00000616250.4, ENST00000367182.8 )
USP7 c.2719-234C>T ( ENST00000344836.9, ENST00000381886.8, ENST00000673704.1 )
MDM4 c.-36+2641G>C ( ENST00000367182.8, ENST00000367183.7, ENST00000391947.6, ENST00000454264.6, ENST00000612738.4, ENST00000614459.4, ENST00000616250.4 ) - Associated Disease
- Malignant neoplasm of prostate
- Source Database
- DisGeNET
- Description
- Both the Mdm4 and Hausp SNPs (rs1380576 and rs1529916) were found to be associated with higher D'Amico risk prostate cancer category at the time of diagnosis (P = 0.023 and P = 0.046, respectively).
- Pubmed
- 20855462
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.123724241339004
- Year of publication
- 2010
Drugs