Annotation Detail

Information
Associated Genes
BSCL2
Associated Variants
HNRNPUL2-BSCL2 c.*506A>G, BSCL2 p.Asn152Ser (p.N152S) ( ENST00000405837.5, ENST00000683296.1, ENST00000403734.2, ENST00000278893.11, ENST00000407022.7, ENST00000684067.1, ENST00000449636.6, ENST00000684475.1, ENST00000682223.1, ENST00000679883.1, ENST00000360796.10, ENST00000421906.5, ENST00000403550.5, ENST00000524862.6 )
HNRNPUL2-BSCL2 c.*506A>G, BSCL2 p.Asn152Ser (p.N152S) ( ENST00000278893.11, ENST00000360796.10, ENST00000403550.5, ENST00000405837.5, ENST00000407022.7, ENST00000421906.5, ENST00000449636.6, ENST00000524862.6, ENST00000679883.1, ENST00000682223.1, ENST00000683296.1, ENST00000684067.1, ENST00000684475.1, ENST00000403734.2 )
Associated Disease
Spastic
Source Database
DisGeNET
Description
The N88S seipin tg mice develop a progressive spastic motor deficit, reactive gliosis in the spinal cord and neurogenic muscular atrophy, recapitulating the symptomatic and pathological phenotype in patients of seipinopathy.
Pubmed
21750110
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Year of publication
2011
Drugs