Annotation Detail
Information
- Associated Genes
- PARP1
- Associated Variants
-
PARP1 MUTATION
PARP1 MUTATION - Associated Disease
- Myeloid Leukemia, Chronic
- Source Database
- DisGeNET
- Description
- The current study demonstrated that treatment of CML cells with 4-MU led to induction of apoptosis through PARP cleavage and loss of mitochondria membrane potential.
- Pubmed
- 26408682
- Section of the abstract supporting the evidence
- RESULTS
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 6
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00108576748832121
Drugs