Annotation Detail

Information
Associated Genes
BCR
Associated Variants
BCR MUTATION
BCR MUTATION
Associated Disease
Myeloid Leukemia, Chronic
Source Database
DisGeNET
Description
Imatinib was the first BCR-ABL1 tyrosine kinase inhibitor (TKI) developed for the treatment of patients with chronic myeloid leukemia (CML); subsequently, the introduction of more potent BCR-ABL1 TKIs has raised expectations regarding the speed and depth of response.
Pubmed
25410137
Section of the abstract supporting the evidence
ALL_TEXT_1/3
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
1
Original source reporting the Gene Disease association
BeFree,CTD_human,GAD,LHGDN,ORPHANET
DisGENET score for the Gene Disease association
0.395567170261351
Drugs