Annotation Detail

Information
Associated Genes
BCR
Associated Variants
BCR MUTATION
BCR MUTATION
Associated Disease
Myeloid Leukemia, Chronic
Source Database
DisGeNET
Description
Chronic myeloid leukemia (CML) involves the malignant transformation of hematopoietic stem cells, defined largely by the Philadelphia chromosome and expression of the breakpoint cluster region-Abelson (BCR-ABL) oncoprotein.
Pubmed
25366930
Section of the abstract supporting the evidence
SIGNIFICANCE
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
1
Original source reporting the Gene Disease association
BeFree,CTD_human,GAD,LHGDN,ORPHANET
DisGENET score for the Gene Disease association
0.395567170261351
Drugs