Annotation Detail

Information
Associated Genes
TAS2R50
Associated Variants
ENSG00000275778 c.-125-12532G>A, TAS2R50 p.Cys203Tyr (p.C203Y) ( ENST00000506868.1, ENST00000703543.1 )
KIF6 p.Trp719Arg (p.W719R) ( ENST00000229913.9, ENST00000287152.12, ENST00000394362.5, ENST00000538893.5 )
ENSG00000275778 c.-125-12532G>A, TAS2R50 p.Cys203Tyr (p.C203Y) ( ENST00000506868.1, ENST00000703543.1 )
KIF6 p.Trp719Arg (p.W719R) ( ENST00000229913.9, ENST00000287152.12, ENST00000394362.5, ENST00000538893.5 )
Associated Disease
Coronary heart disease
Source Database
DisGeNET
Description
Our data indicate that the assessment of KIF6 rs20455 and TAS2R50 rs1376251 genotypes are not useful for predicting statin induced cardiovascular risk reduction in men, but do predict CHD risk reduction in women in this elderly population.
Pubmed
22192511
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00263847385068233
Year of publication
2012
Drugs