Annotation Detail

Information
Associated Genes
WRN
Associated Variants
WRN p.Cys1367Arg (p.C1367R) ( ENST00000298139.7 )
WRN p.Cys1367Arg (p.C1367R) ( ENST00000298139.7 )
Associated Disease
malignant fibrous histiocytoma
Source Database
DisGeNET
Description
An exploratory subgroup analysis without multiple comparison adjustment suggested that the WRN-Cys1367Arg SNP is associated with soft tissue sarcomas, sarcomas with reciprocal chromosomal translocations and malignant fibrous histiocytoma.
Pubmed
18271933
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00299579211454747
Year of publication
2008
Drugs