Annotation Detail
Information
- Associated Genes
- TP53
- Associated Variants
-
WRN p.Cys1367Arg (p.C1367R)
(
ENST00000298139.7 )
WRN p.Cys1367Arg (p.C1367R) ( ENST00000298139.7 ) - Associated Disease
- Malignant neoplasm of breast
- Source Database
- DisGeNET
- Description
- The joint effect of WRN Cys1367Arg and p53 MspI resulted in an increased breast cancer risk compared to the single polymorphisms (OR = 3.39, 95% CI 1.19-9.71).
- Pubmed
- 16501249
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.24
- Year of publication
- 2006
Drugs