Annotation Detail

Information
Associated Genes
MC4R
Associated Variants
MC4R p.Gly181Asp (p.G181D) ( ENST00000299766.5 )
MC4R p.Arg165Trp (p.R165W) ( ENST00000299766.5 )
MC4R p.Gly181Asp (p.G181D) ( ENST00000299766.5 )
MC4R p.Arg165Trp (p.R165W) ( ENST00000299766.5 )
Associated Disease
obesity
Source Database
DisGeNET
Description
This study shows a carrier frequency of 2.5% of pathogenic mutations in the MC4R gene in a population-based study of obese men.
Pubmed
15486053
Original source reporting the Gene Disease association
UNIPROT
DisGENET score for the Gene Disease association
0.790574886740879
Year of publication
2005
Drugs