Annotation Detail

Information
Associated Genes
IDH2
Associated Variants
IDH2 MUTATION
IDH2 MUTATION
Associated Disease
Leukemia, Myelocytic, Acute
Source Database
DisGeNET
Description
As the genetic landscape of AML has been mapped, other attractive targets for therapy have been discovered, including C-KIT, IDH1 and IDH2, NPM1, and MEK.
Pubmed
26111466
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
5
Original source reporting the Gene Disease association
BeFree,GAD
DisGENET score for the Gene Disease association
0.0357656518977951
Drugs