Annotation Detail

Information
Associated Genes
TET2
Associated Variants
TET2 MUTATION
TET2 MUTATION
Associated Disease
Leukemia, Myelocytic, Acute
Source Database
DisGeNET
Description
Our results also provide an explanation for the mutual exclusivity of WT1 and TET2 mutations in AML, and suggest an IDH1/2-TET2-WT1 pathway in suppressing AML.
Pubmed
25601757
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
8
Original source reporting the Gene Disease association
BeFree,GAD
DisGENET score for the Gene Disease association
0.0612375806116254
Drugs