Annotation Detail
Information
- Associated Genes
- MRTFA
- Associated Variants
-
MRTFA MUTATION
MRTFA MUTATION - Associated Disease
- Acute Megakaryocytic Leukemias
- Source Database
- DisGeNET
- Description
- Phagocytosis of ACs by splenic MZMs required the megakaryoblastic leukemia 1 (MKL1) transcriptional coactivator-mediated mechanosensing pathway, which was maintained by MZ B cells through expression of membrane lymphotoxin-α1β2 (mLT).
- Pubmed
- 26098211
- Section of the abstract supporting the evidence
- ALL_TEXT_2/3
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 3
- Original source reporting the Gene Disease association
- BeFree,LHGDN
- DisGENET score for the Gene Disease association
- 0.00815318768407324
Drugs