Annotation Detail

Information
Associated Genes
MRTFA
Associated Variants
MRTFA MUTATION
MRTFA MUTATION
Associated Disease
Acute Megakaryocytic Leukemias
Source Database
DisGeNET
Description
We demonstrate here that the transcriptional modulator megakaryocytic leukemia 1 (MKL1) was activated by hypoxia and transforming growth factor (TGF-β), two prominent pro-malignancy factors, in cultured lung cancer cells.
Pubmed
25746000
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
4
Original source reporting the Gene Disease association
BeFree,LHGDN
DisGENET score for the Gene Disease association
0.00815318768407324
Drugs