Annotation Detail

Information
Associated Genes
NCF4
Associated Variants
NCF4 c.32+1258T>C ( ENST00000248899.11, ENST00000397147.7, ENST00000650827.1 )
rs13361189
rs4958847
NCF4 c.32+1258T>C ( ENST00000248899.11, ENST00000397147.7, ENST00000650827.1 )
rs13361189
rs4958847
Associated Disease
Inflammatory Bowel Diseases
Source Database
DisGeNET
Description
NCF4 and IRGM were significantly associated with ileal CD (P-value(rs4821544)=0.0090, odds ratio (OR)=1.425, 95% confidence interval (CI): 1.092-1.859; P-value(rs13361189)=0.0017, OR=1.942, 95% CI: 1.274-2.959; P-value(rs4958847)=0.0022, OR=1.767, 95% CI: 1.224-2.558), but not with other forms of inflammatory bowel disease (IBD).
Pubmed
18580884
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00263847385068233
Year of publication
2008
Drugs