Annotation Detail
Information
- Associated Genes
- MAP3K1
- Associated Variants
-
LSP1 c.*13+200T>C
(
ENST00000381775.5,
ENST00000311604.8,
ENST00000612798.4,
ENST00000405957.6,
ENST00000406638.6 )
rs2107425
FLACC1 p.Thr397= (p.T397=) ( ENST00000696069.1, ENST00000286190.9, ENST00000392257.8, ENST00000405148.6, ENST00000439709.5 )
rs889312
rs13281615 ( ENST00000645438.1 )
LSP1 c.*13+200T>C ( ENST00000311604.8, ENST00000381775.5, ENST00000405957.6, ENST00000406638.6, ENST00000612798.4 )
rs2107425
FLACC1 p.Thr397= (p.T397=) ( ENST00000696069.1, ENST00000286190.9, ENST00000392257.8, ENST00000405148.6, ENST00000439709.5 )
rs889312
rs13281615 ( ENST00000645438.1 ) - Associated Disease
- Malignant neoplasm of breast
- Source Database
- DisGeNET
- Description
- Consistent with their breast cancer associations, rs3817198 (LSP1) and rs13281615 (8q) were associated with dense area and percent dense area (all P(x) and P(c) <0.05), and rs889312 (MAP3K1), rs2107425 (H19), and rs17468277 (CASP8) were marginally associated with dense area (some P(x) or P(c) <0.05).
- Pubmed
- 20145138
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.166482706694081
- Year of publication
- 2010
Drugs