Annotation Detail

Information
Associated Genes
INS
Associated Variants
SLC30A8 p.Arg325Trp (p.R325W) ( ENST00000427715.2, ENST00000456015.7, ENST00000519688.5, ENST00000521243.5 )
SLC30A8 p.Arg325Trp (p.R325W) ( ENST00000456015.7, ENST00000519688.5, ENST00000521243.5, ENST00000427715.2 )
Associated Disease
diabetes mellitus
Source Database
DisGeNET
Description
Association of the SLC30A8 missense polymorphism R325W with proinsulin levels at baseline and after lifestyle, metformin or troglitazone intervention in the Diabetes Prevention Program.
Pubmed
21779873
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.295274146663208
Year of publication
2011
Drugs