Annotation Detail

Information
Associated Genes
BTK
Associated Variants
BTK MUTATION
BTK MUTATION
Associated Disease
chronic lymphocytic leukemia
Source Database
DisGeNET
Description
Expression of functional sphingosine-1 phosphate receptor-1 is reduced by B cell receptor signaling and increased by inhibition of PI3 kinase δ but not SYK or BTK in chronic lymphocytic leukemia cells.
Pubmed
25632006
Section of the abstract supporting the evidence
TITLE
Number of the section of the abstract supporting the evidence
0
Number of the sentence supporting the evidence
0
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00380018620912425
Drugs