Annotation Detail

Information
Associated Genes
SF3B2
Associated Variants
SF3B2 MUTATION
SF3B2 MUTATION
Associated Disease
chronic lymphocytic leukemia
Source Database
DisGeNET
Description
Although TP53, NOTCH1, and SF3B1 mutations may impair prognosis of patients with chronic lymphocytic leukemia (CLL) receiving frontline therapy, the impact of these mutations or any other, alone or in combination, remains unclear at relapse.
Pubmed
26316624
Section of the abstract supporting the evidence
ALL_TEXT_1/3
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
1
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00651460492992728
Drugs