Annotation Detail

Information
Associated Genes
ZAP70
Associated Variants
ZAP70 MUTATION
ZAP70 MUTATION
Associated Disease
chronic lymphocytic leukemia
Source Database
DisGeNET
Description
This represents the likelihood of tyrosine kinase inhibitors being effective targeted treatments for ZAP-70+ CLL cells.
Pubmed
25275600
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
12
Original source reporting the Gene Disease association
BeFree,LHGDN
DisGENET score for the Gene Disease association
0.0796615783011627
Drugs