Annotation Detail

Information
Associated Genes
IDH1
Associated Variants
IDH1 MUTATION
IDH1 MUTATION
Associated Disease
leukemia
Source Database
DisGeNET
Description
Our study provides proof of concept for the molecular and biological activity of novel allosteric inhibitors for targeting different mutant forms of IDH1 in leukemia.
Pubmed
26436839
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
6
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00434306995328485
Drugs