Annotation Detail
Information
- Associated Genes
- GSTM1
- Associated Variants
-
CYP2E1 c.-117-695G>C
(
ENST00000463117.6 )
CYP2E1 c.-117-455C>T ( ENST00000463117.6 )
GSTP1 c.[313A>G;341=] ( ENST00000398606.10 )
ERCC2 p.Lys751Ter (p.K751*) ( ENST00000391944.8, ENST00000391945.10, ENST00000684407.1 )
ERCC2 p.Lys751Gln (p.K751Q) ( ENST00000391944.8, ENST00000391945.10, ENST00000684407.1 )
CYP2E1 c.-117-695G>C ( ENST00000463117.6 )
CYP2E1 c.-117-455C>T ( ENST00000463117.6 )
GSTP1 c.[313A>G;341=] ( ENST00000398606.10 )
ERCC2 p.Lys751Ter (p.K751*) ( ENST00000391944.8, ENST00000391945.10, ENST00000684407.1 )
ERCC2 p.Lys751Gln (p.K751Q) ( ENST00000391944.8, ENST00000391945.10, ENST00000684407.1 ) - Associated Disease
- Malignant neoplasm of mouth
- Source Database
- DisGeNET
- Description
- GSTT1 null and rs1695 were inversely associated with oral leukoplakia while GSTM1 null, GSTT1 null, rs2031920, rs3813867 (CYP2E1), and rs13181 were associated with OC.
- Pubmed
- 21741876
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0163301195865364
- Year of publication
- 2011
Drugs