Annotation Detail
Information
- Associated Genes
- STAT5A
- Associated Variants
-
STAT5A MUTATION
STAT5A MUTATION - Associated Disease
- leukemia
- Source Database
- DisGeNET
- Description
- Forced expression of STAT5A in leukemia cells caused hypermethylation on the promoter region of the tumor suppressor gene, PTEN, and downregulated its mRNA levels, as measured by methylation-specific and real-time polymerase chain reaction, respectively.
- Pubmed
- 26059451
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 8
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00651460492992728
Drugs