Annotation Detail
Information
- Associated Genes
- FLT3
- Associated Variants
-
FLT3 MUTATION
FLT3 MUTATION - Associated Disease
- leukemia
- Source Database
- DisGeNET
- Description
- RNA interference against FLT3-ITD reduced cytotoxic effect and apoptosis induced by C-1311, indicating selective inhibition of FLT3-ITD crucial for high efficacy of drug against activated leukemia cells.
- Pubmed
- 25896848
- Section of the abstract supporting the evidence
- ALL_TEXT_2/3
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 6
- Original source reporting the Gene Disease association
- BeFree,GAD,LHGDN
- DisGENET score for the Gene Disease association
- 0.0932786172985476
Drugs