Annotation Detail

Information
Associated Genes
BRCA1
Associated Variants
RAD51B c.757-59007C>T ( ENST00000460526.6, ENST00000488612.5, ENST00000487861.5, ENST00000471583.6, ENST00000487270.5 )
rs1562430 ( ENST00000645438.1 )
RAD51B c.757-59007C>T ( ENST00000460526.6, ENST00000471583.6, ENST00000487270.5, ENST00000487861.5, ENST00000488612.5 )
rs1562430 ( ENST00000645438.1 )
Associated Disease
Malignant neoplasm of breast
Source Database
DisGeNET
Description
Furthermore, we showed that the SNPs rs1562430/8q24.21 and rs1314913/14q24.1 strongly influence BC risk in men and suggested that the SNP rs1314913/14q24.1 may act as a risk modifier locus in male BRCA1/2 mutation carriers.
Pubmed
26248686
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.36
Year of publication
2015
Drugs