Annotation Detail
Information
- Associated Genes
- FOXP2
- Associated Variants
-
FOXP2 MUTATION
FOXP2 MUTATION - Associated Disease
- Speech and language disorder
- Source Database
- DisGeNET
- Description
- We show that TBR1 homodimerizes, that it interacts with FOXP2, a transcription factor implicated in speech/language disorders, and that this interaction is disrupted by pathogenic mutations affecting either protein.
- Pubmed
- 25232744
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 6
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00760037241824849
Drugs