Annotation Detail

Information
Associated Genes
PTPN22
Associated Variants
RSBN1 p.Arg31= (p.R31=) ( ENST00000612242.4, ENST00000261441.9 )
RSBN1 p.Arg31= (p.R31=) ( ENST00000612242.4, ENST00000261441.9 )
PTPN22 c.2054-852T>C ( ENST00000528414.5, ENST00000420377.6, ENST00000525799.1, ENST00000538253.5, ENST00000359785.10, ENST00000460620.5 )
RSBN1 p.Arg31= (p.R31=) ( ENST00000261441.9, ENST00000612242.4 )
RSBN1 p.Arg31= (p.R31=) ( ENST00000261441.9, ENST00000612242.4 )
PTPN22 c.2054-852T>C ( ENST00000359785.10, ENST00000420377.6, ENST00000460620.5, ENST00000525799.1, ENST00000528414.5, ENST00000538253.5 )
Associated Disease
rheumatoid arthritis
Source Database
DisGeNET
Description
We compared the allele frequencies of five haplotype-tagging SNPs in the PTPN22 gene, 2 of which are reportedly associated with RA in Caucasians (rs3789604 and rs1310182), and compared haplotype distributions between 184 Japanese T1D patients and 179 healthy controls.
Pubmed
20510318
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.524345610778177
Year of publication
2010
Drugs