Annotation Detail

Information
Associated Genes
IFNL3
Associated Variants
NC_000019.10:g.39252525T>G
INPP5D c.2887+932A>G ( ENST00000359570.9, ENST00000445964.6 )
NC_000019.10:g.39252525T>G
INPP5D c.2975+932A>G ( ENST00000359570.9, ENST00000445964.6 )
Associated Disease
Hepatitis C, Chronic
Source Database
DisGeNET
Description
The set of odds ratios of studies demonstrated an association between SNP (rs12987960/rs8099917) in the IL28B and SVR in CHC treated with peginterferon plus ribavirin (OR: 4.6; 95% CI: 2.9-7.3).
Pubmed
21382156
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0948429671860937
Year of publication
2011
Drugs