Annotation Detail

Information
Associated Genes
IFNL3
Associated Variants
IFNL4 c.151-152G>A ( ENST00000606380.2 )
IFNL4 c.151-152G>A ( ENST00000606380.2 )
Associated Disease
liver cirrhosis
Source Database
DisGeNET
Description
Recently, the rs12979860 C/T polymorphism in the IL28B gene has been linked to progression towards cirrhosis in HCV mono-infected patients and to treatment response of HCV-infection in HIV/HCV co-infected patients.
Pubmed
21813376
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00833875316436871
Year of publication
2011
Drugs