Annotation Detail

Information
Associated Genes
IFNL3
Associated Variants
IFNL3 p.Lys74Arg (p.K74R) ( ENST00000413851.3, ENST00000613087.5 )
IFNL4 c.151-152G>A ( ENST00000606380.2 )
NC_000019.10:g.39252525T>G
IFNL3 p.Lys74Arg (p.K74R) ( ENST00000413851.3, ENST00000613087.5 )
IFNL4 c.151-152G>A ( ENST00000606380.2 )
NC_000019.10:g.39252525T>G
Associated Disease
Coinfection
Source Database
DisGeNET
Description
We tested the association of spontaneous clearance and three single nucleotide polymorphisms (SNPs) near the Interferon-lambda 3 (IFNL3) gene (rs12979860, rs8099917, functional variant rs8103142) and compared the SNP frequencies between HIV-HCV co-infected whites and Aboriginals from the Canadian Co-infection Cohort.
Pubmed
25803108
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00217153497664243
Year of publication
2015
Drugs