Annotation Detail

Information
Associated Genes
AGTR1
Associated Variants
AGTR1 MUTATION
AGTR1 MUTATION
Associated Disease
Kidney Diseases
Source Database
DisGeNET
Description
Angiotensin II, acting through its AT1 receptor, plays a critical role in generation of proteinuria and progression of kidney injury in a number of kidney diseases, including FSGS.
Pubmed
26551740
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
7
Original source reporting the Gene Disease association
BeFree,CTD_human,CTD_mouse,GAD
DisGENET score for the Gene Disease association
0.221183735675579
Drugs