Annotation Detail
Information
- Associated Genes
- IFNL3
- Associated Variants
-
IFNL4 c.151-152G>A
(
ENST00000606380.2 )
IFNL4 c.151-152G>A ( ENST00000606380.2 ) - Associated Disease
- Fibrosis, Liver
- Source Database
- DisGeNET
- Description
- The IL28B rs12979860 CC genotype is associated with a higher prevalence of cirrhosis in HIV-HCV-coinfected patients than CT/TT genotypes, suggesting that IL28B CC carriers may experience a more rapid progression of HCV-related liver fibrosis, perhaps as result of increased liver inflammation.
- Pubmed
- 21592993
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00760037241824849
- Year of publication
- 2011
Drugs