Annotation Detail

Information
Associated Genes
CAD
Associated Variants
LPA c.3947+467T>C ( ENST00000316300.10 )
LPA c.3947+467T>C ( ENST00000316300.10 )
Associated Disease
coronary artery disease
Source Database
DisGeNET
Description
The LPA single-nucleotide polymorphism rs10455872 has been associated with low-density lipoprotein cholesterol (LDLc) lowering response to statins in several randomized control trials (RCTs) and is a known coronary artery disease (CAD) marker.
Pubmed
23903772
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00488595369744546
Year of publication
2014
Drugs