Annotation Detail

Information
Associated Genes
IFNL3
Associated Variants
IFNL4 INDEL ( ENST00000606380.2 )
IFNL4 INDEL ( ENST00000606380.2 )
IFNL4 c.151-152G>A ( ENST00000606380.2 )
NC_000019.10:g.39252525T>G
IFNL4 c.151-152G>A ( ENST00000606380.2 )
NC_000019.10:g.39252525T>G
Associated Disease
Hepatitis C, Chronic
Source Database
DisGeNET
Description
Recent studies in chronic hepatitis C patients have shown that rs368234815 polymorphism nearby IL28B is a better predictor of response to antiviral treatment with pegylated interferon and ribavirin than IL28B polymorphisms (rs12979860 and rs8099917).
Pubmed
25130512
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0948429671860937
Year of publication
2014
Drugs