Annotation Detail

Information
Associated Genes
IFNL3
Associated Variants
IFNL4 c.151-152G>A ( ENST00000606380.2 )
IFNL4 c.151-152G>A ( ENST00000606380.2 )
Associated Disease
hepatitis B
Source Database
DisGeNET
Description
In recipients carrying rs12979860 IL-28B C/C genotype the use of cyclosporine seems to contribute to enhance the probability of developing biliary complications which in hepatitis B and C positives appear to reduce patient survival.
Pubmed
25219480
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00895758177865001
Year of publication
2014
Drugs