Annotation Detail

Information
Associated Genes
IFNL3
Associated Variants
IFNL4 c.151-152G>A ( ENST00000606380.2 )
IFNL4 c.151-152G>A ( ENST00000606380.2 )
Associated Disease
Virus Diseases
Source Database
DisGeNET
Description
The interleukin-28B (IL28B) gene contains a single-nucleotide polymorphism at location rs12979860 that affects both the natural history of hepatitis C virus infection and the patient's response to treatment, particularly interferon-based regimens with or without protease inhibitors.
Pubmed
25897598
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00950046552281062
Year of publication
2015
Drugs