Annotation Detail

Information
Associated Genes
IFNL3
Associated Variants
IFNL4 c.151-152G>A ( ENST00000606380.2 )
IFNL4 c.151-152G>A ( ENST00000606380.2 )
Associated Disease
hepatitis C
Source Database
DisGeNET
Description
Genetic variation of interleukin-28B (IL-28B) rs12979860 T/C polymorphism is associated with the immune response to interferon (IFN) therapy, which is applied in the treatment of chronic viral hepatitis induced by hepatitis B virus (HBV) and hepatitis C virus (HCV).
Pubmed
24874053
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.220488369584746
Year of publication
2014
Drugs