Annotation Detail

Information
Associated Genes
FGFR3
Associated Variants
FGFR3 MUTATION
FGFR3 MUTATION
Associated Disease
seborrheic keratosis
Source Database
DisGeNET
Description
The results of this study suggest that activating mutations of EGFR, HRAS, and KRAS contribute to the pathogenesis of human SK, although at a lower frequency than FGFR3 and PIK3CA mutations.
Pubmed
23739246
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
11
Original source reporting the Gene Disease association
BeFree,CLINVAR,LHGDN,UNIPROT
DisGENET score for the Gene Disease association
0.255240470923153
Drugs