Annotation Detail

Information
Associated Genes
IFNL3
Associated Variants
rs12980275
IFNL4 c.151-152G>A ( ENST00000606380.2 )
NC_000019.10:g.39252525T>G
rs12980275
IFNL4 c.151-152G>A ( ENST00000606380.2 )
NC_000019.10:g.39252525T>G
Associated Disease
Hepatitis C, Chronic
Source Database
DisGeNET
Description
With the screening for IL28B polymorphisms rs12980275, rs8099917 and rs12979860, which are associated with HCV chronicity and with reduced SVR rates, an important prognostic factor of the therapy of chronic hepatitis C can be easily diagnosed.
Pubmed
21149916
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0948429671860937
Year of publication
2010
Drugs