Annotation Detail

Information
Associated Genes
IFNL3
Associated Variants
IFNL4 c.151-152G>A ( ENST00000606380.2 )
IFNL4 c.151-152G>A ( ENST00000606380.2 )
Associated Disease
hepatitis C
Source Database
DisGeNET
Description
The rs12979860 CC genotype of the interleukin 28B (IL28B) polymorphism is associated with high rates of sustained virological response (SVR) to peginterferon (PegIFN) and ribavirin (Rbv) in hepatitis C virus genotype-1 (HCV-1) patients.
Pubmed
23936821
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.220488369584746
Year of publication
2013
Drugs