Annotation Detail
Information
- Associated Genes
- IFNL3
- Associated Variants
-
IFNL4 c.151-152G>A
(
ENST00000606380.2 )
IFNL4 c.151-152G>A ( ENST00000606380.2 ) - Associated Disease
- Acute hepatitis C
- Source Database
- DisGeNET
- Description
- The single-nucleotide polymorphism rs12979860 near IFNL3 (previously known as IL28B) is important in response to IFN-α treatment and in spontaneous resolution of acute hepatitis C. The role of the IFNL3 polymorphism in NK cell function is unclear.
- Pubmed
- 26034208
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00325730246496364
- Year of publication
- 2015
Drugs