Annotation Detail

Information
Associated Genes
IFNL3
Associated Variants
IFNL4 c.151-152G>A ( ENST00000606380.2 )
NC_000019.10:g.39252525T>G
IFNL4 c.151-152G>A ( ENST00000606380.2 )
NC_000019.10:g.39252525T>G
Associated Disease
HIV Infections
Source Database
DisGeNET
Description
Polymorphisms of rs12979860 and rs8099917 near IL28B only associate with the treatment response to PegIFN/RBV in patients infected with HCV genotype 1 or 4 but not with genotype 2 or 3, irrespective of the previous treatment history or HIV co-infected status.
Pubmed
23029188
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0325842943029521
Year of publication
2012
Drugs